Product Datasheet  
HMGB2 Antibody  
Catalog Number: 31219  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:O14746
    Gene ID:7015
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 166-180 amino acids of Human high mobility group box 2
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 24kd
    ELISA: 1:1000-1:10000
    Western blotting: 1:2000-1:5000

  • other_names：  
  • high mobility group box 2, HMG2
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total HMGB2 protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.




 
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