HMGA2 Antibody

Catalog Number:

31218

Amount:

100μg

Price:

$319

Swiss-Prot No:

Genbank No.: NP_003474

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 59-72 amino acids of Human high mobility group AT-hook 2

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total HMGA2 protein.

Applications:

ELISA WB

Background:

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Predicted MW: 12kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF