Product Datasheet  
HMGA2 Antibody  
Catalog Number: 31218  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Genbank No.: NP_003474
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 59-72 amino acids of Human high mobility group AT-hook 2
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 12kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000

  • other_names：  
  • high mobility group AT-hook 2, BABL, LIPO, HMGIC, HMGI-C, STQTL9
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total HMGA2 protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.




 
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