HDAC1 Antibody

Catalog Number:

31215

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P26583
Gene ID:3148

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 469-482 amino acids of Human histone deacetylase 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total HDAC1 protein.

Applications:

ELISA WB IHC

Background:

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

References:

appl_detail:

Predicted MW: 55kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF