Product Datasheet  
HDAC1 Antibody  
Catalog Number: 31215  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P26583
    Gene ID:3148
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 469-482 amino acids of Human histone deacetylase 1
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Predicted MW: 55kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • histone deacetylase 1, HD1, RPD3, GON-10, RPD3L1
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total HDAC1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.



 
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