GFRA3 Antibody

Catalog Number:

31207

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P46095
Gene ID:2830

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 346-359 amino acids of Human GDNF family receptor alpha 3

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total GFRA3 protein.

Applications:

ELISA WB

Background:

GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

References:

appl_detail:

Predicted MW: 44kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:2000

Datasheet PDF