Product Datasheet
GFRA3 Antibody
Catalog Number: 31207
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P46095
Gene ID:2830
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 346-359 amino acids of Human GDNF family receptor alpha 3
- appl_detail:
- Predicted MW: 44kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:2000
- other_names:
- GDNF family receptor alpha 3
- Specificity:
- The antibody detects endogenous level of total GFRA3 protein.
- Background:
- GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.
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