EPOR Antibody

Catalog Number:

31195

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P07951
Gene ID:7169

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 31-45 amino acids of Human erythropoietin receptor

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total EPOR protein.

Applications:

ELISA WB

Background:

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

Predicted MW: 55kd
ELISA: 1:1000-1:5000
Western blotting: 1:1000-1:5000

Datasheet PDF