Product Datasheet  
EPOR Antibody  
Catalog Number: 31195  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P07951
    Gene ID:7169
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 31-45 amino acids of Human erythropoietin receptor
  • reactivity：  
  • Hu Rt
  • appl_detail：  

  • Predicted MW: 55kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:1000-1:5000

  • other_names：  
  • erythropoietin receptor, EPO-R
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total EPOR protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.




 
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