DNM1 Antibody

Catalog Number:

31186

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q15223
Gene ID:5818

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 850-863 amino acids of Human Dynamin-1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total DNM1 protein.

Applications:

ELISA WB

Background:

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

References:

appl_detail:

Predicted MW: 97kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF