Product Datasheet  
DNM1 Antibody  
Catalog Number: 31186  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q15223
    Gene ID:5818
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from 850-863 amino acids of Human Dynamin-1
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Predicted MW: 97kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000

  • other_names:  
  • Dynamin-1, DNM
  • Purification:  
  • Specificity:  
  • The antibody detects endogenous level of total DNM1 protein.
  • Applications:  
  • ELISA WB
  • Background:  
  • This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.




 
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