CRMP1 Antibody

Catalog Number:

31173

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P57773
Gene ID:81025

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 507-522 amino acids of Human collapsin response mediator protein 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CRMP1 protein.

Applications:

ELISA WB IHC

Background:

Collapsin response mediator protein 1, encoded by the?CRMP1?gene, is a human?protein?of the?CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.

References:

appl_detail:

Predicted MW: 62kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF