Product Datasheet
CRMP1 Antibody
Catalog Number: 31173
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P57773
Gene ID:81025
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 507-522 amino acids of Human collapsin response mediator protein 1
- other_names:
- collapsin response mediator protein 1, DRP1, DRP-1, CRMP-1, DPYSL1, ULIP-3
- Specificity:
- The antibody detects endogenous level of total CRMP1 protein.
- Applications:
- ELISA WB IHC
- Background:
Collapsin response mediator protein 1, encoded by the?CRMP1?gene, is a human?protein?of the?CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.
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