AVEN Antibody

Catalog Number:

31160

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P51532
Gene ID:6597

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 339-353 amino acids of Human Apoptosis, caspase activation inhibitor

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total AVEN protein.

Applications:

ELISA WB

Background:

Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus .

References:

appl_detail:

Predicted MW: 39kd
ELISA: 1:500-1:5000
Western blotting: 1:500-1:1000

Datasheet PDF