Product Datasheet  
AVEN Antibody  
Catalog Number: 31160  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P51532
    Gene ID:6597
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 339-353 amino acids of Human Apoptosis, caspase activation inhibitor
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 39kd
    ELISA: 1:500-1:5000
    Western blotting: 1:500-1:1000

  • other_names：  
  • Apoptosis, caspase activation inhibitor, PDCD12
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total AVEN protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus .




 
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