ADAMTS5 Antibody

Catalog Number:

31158

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UNA0
Gene ID:27113

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 529-541 amino acids of Human A disintegrin and metalloproteinase with thrombospondin motifs 5

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ADAMTS5 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

References:

appl_detail:

Predicted MW: 102kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50

Datasheet PDF