Product Datasheet
ADAMTS5 Antibody
Catalog Number: 31158
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9UNA0
Gene ID:27113
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 529-541 amino acids of Human A disintegrin and metalloproteinase with thrombospondin motifs 5
- other_names:
- A disintegrin and metalloproteinase with thrombospondin motifs 5, ADMP-2, ADAM-TS5, ADAMTS-5, ADAMTS11, ADAM-TS 5, ADAMTS-11, ADAM-TS 11
- Specificity:
- The antibody detects endogenous level of total ADAMTS5 protein.
- Applications:
- ELISA WB IHC
- Background:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.
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