RHOB Antibody

Catalog Number:

31144

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P20339
Gene ID:5868

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 179-188 amino acids of Human Ras homolog family member B

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total RHOB protein.

Applications:

ELISA WB

Background:

Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

References:

appl_detail:

Predicted MW: 22kd
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:2000

Datasheet PDF