Product Datasheet  
RHOB Antibody  
Catalog Number: 31144  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P20339
    Gene ID:5868
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 179-188 amino acids of Human Ras homolog family member B
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Predicted MW: 22kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:2000
  • other_names：  
  • Ras homolog family member B, ARH6, ARHB, RHOH6
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total RHOB protein.
  • Applications：  
  • ELISA WB
  • Background：  
  • Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.



 
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