ADRB2 Antibody

Catalog Number:

31142

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P84077
Gene ID:375

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 21-33 amino acids of Human adrenoceptor beta 2, surface

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ADRB2 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.?

References:

appl_detail:

Predicted MW: 46kd
ELISA: 1:1000-1:2000
Western blotting: 1:1000-1:2000
Immunohistochemistry: 1:15-1:50

Datasheet PDF