Product Datasheet  
ADRB2 Antibody  
Catalog Number: 31142  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P84077
    Gene ID:375
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 21-33 amino acids of Human adrenoceptor beta 2, surface
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 46kd
    ELISA: 1:1000-1:2000
    Western blotting: 1:1000-1:2000
    Immunohistochemistry: 1:15-1:50
  • other_names：  
  • Adrenoceptor beta 2, surface, BAR, B2AR, ADRBR, ADRB2R, BETA2AR
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total ADRB2 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.?



 
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