SOX2 Antibody

Catalog Number:

31128

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P13726
Gene ID:2152

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 250 amino acids of human SRY (sex determining region Y)-box 2

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total SOX2 protein.

Applications:

ELISA WB IHC

Background:

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

References:

appl_detail:

Predicted MW: 34kd
ELISA: 1:1000-1:2000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50

Datasheet PDF