Product Datasheet
SOX2 Antibody
Catalog Number: 31128
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P13726
Gene ID:2152
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to C terminal 250 amino acids of human SRY (sex determining region Y)-box 2
- other_names:
- SRY (sex determining region Y)-box 2, ANOP3; MCOPS3
- Specificity:
- The antibody detects endogenous level of total SOX2 protein.
- Applications:
- ELISA WB IHC
- Background:
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
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