PEG10 Antibody

Catalog Number:

31112

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P07737
Gene ID:5216

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 250 amino acids of human paternally expressed 10

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PEG10 protein.

Applications:

ELISA WB

Background:

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

References:

appl_detail:

Predicted MW: 80kd
ELISA: 1:1000-1:5000
Western blotting: 1:400

Datasheet PDF