Product Datasheet  
PEG10 Antibody  
Catalog Number: 31112  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P07737
    Gene ID:5216
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to C terminal 250 amino acids of human paternally expressed 10
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 80kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:400
  • other_names：  
  • paternally expressed 10, EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total PEG10 protein.
  • Applications：  
  • ELISA WB
  • Background：  
  • This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.



 
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