PDCD10 Antibody

Catalog Number:

31110

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q7Z3Z4
Gene ID:143689

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PDCD10 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

References:

appl_detail:

Predicted MW: 25kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF