Product Datasheet  
PDCD10 Antibody  
Catalog Number: 31110  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q7Z3Z4
    Gene ID:143689
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 25kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100
  • other_names：  
  • programmed cell death 10, CCM3, TFAR15
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total PDCD10 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.



 
© Signalway Biotechnology All Rights Reserved.