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CDH23 Antibody

Catalog Number:

31109
other_names: cadherin-related 23, USH1D, CDHR23

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q86TG7
Gene ID:23089

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 250 amino acids of human cadherin-related 23cadherin-related 23

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CDH23 protein.

Applications:

ELISA WB IHC

Background:

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.

References:

appl_detail:

Predicted MW: 45kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300

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