Product Datasheet
CDH23 Antibody
Catalog Number: 31109
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q86TG7
Gene ID:23089
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to C terminal 250 amino acids of human cadherin-related 23cadherin-related 23
- other_names:
- cadherin-related 23, USH1D, CDHR23
- Specificity:
- The antibody detects endogenous level of total CDH23 protein.
- Applications:
- ELISA WB IHC
- Background:
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
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