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SPP1 Antibody

Catalog Number:

31106
other_names: secreted phosphoprotein 1, OPN, BNSP, BSPI, ETA-1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9H251
Gene ID:64072

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 17-300 amino acids of human secreted phosphoprotein 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total SPP1 protein.

Applications:

ELISA WB

Background:

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Predicted MW: 34kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

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