Product Datasheet  
SPP1 Antibody  
Catalog Number: 31106  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q9H251
    Gene ID:64072
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein corresponding to a region derived from 17-300 amino acids of human secreted phosphoprotein 1
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Predicted MW: 34kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
  • other_names:  
  • secreted phosphoprotein 1, OPN, BNSP, BSPI, ETA-1
  • Purification:  
  • Specificity:  
  • The antibody detects endogenous level of total SPP1 protein.
  • Applications:  
  • ELISA WB
  • Background:  
  • The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.



 
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