ITGB3BP Antibody

Catalog Number:

31091

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13257
Gene ID:4085

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ITGB3BP protein.

Applications:

ELISA WB

Background:

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

Predicted MW: 15kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000

Datasheet PDF