Product Datasheet  
ITGB3BP Antibody  
Catalog Number: 31091  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q13257
    Gene ID:4085
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 15kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:200-1:1000

  • other_names：  
  • integrin beta 3 binding protein (beta3-endonexin), CENPR, NRIF3, TAP20, CENP-R, HSU37139
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total ITGB3BP protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.




 
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