AIF1 Antibody

Catalog Number:

31086

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q14116
Gene ID:3606

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total AIF1 protein.

Applications:

ELISA WB IHC

Background:

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.?Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

References:

appl_detail:

Predicted MW: 17kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF