Product Datasheet  
AIF1 Antibody  
Catalog Number: 31086  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q14116
    Gene ID:3606
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 17kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:200-1:1000
    Immunohistochemistry: 1:25-1:100

  • other_names：  
  • allograft inflammatory factor 1, IBA1, IRT1, AIF-1, IRT-1
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total AIF1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.?Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.




 
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