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Catalog Number: |
31079 |
| other_names: | complement factor H-related 1, CFHL, FHR1, HFL1, HFL2, CFHL1, H36-1, H36-2, CFHL1P, CFHR1P |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Genbank No.: BC016755 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to a region derived from 22-330 amino acids of human complement factor H-related 1 |
Purification: |
|
Specificity/Sensitivity: |
The antibody detects endogenous level of total CFHR1 protein. |
Applications: |
ELISA WB IHC |
Background: |
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.? |
References: |
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appl_detail: |
Predicted MW: 38kd |
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