Product Datasheet  
CFHR1 Antibody  
Catalog Number: 31079  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Genbank No.: BC016755
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 22-330 amino acids of human complement factor H-related 1
  • reactivity：  
  • Hu
  • appl_detail：  

  • Predicted MW: 38kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • complement factor H-related 1, CFHL, FHR1, HFL1, HFL2, CFHL1, H36-1, H36-2, CFHL1P, CFHR1P
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CFHR1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.?




 
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