EGR1 Antibody

Catalog Number:

31068

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O43638
Gene ID:2307

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 87-337 amino acids of human early growth response 1early growth response 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total EGR1 protein.

Applications:

ELISA WB

Background:

EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).

References:

appl_detail:

Predicted MW: 58kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000

Datasheet PDF