Product Datasheet
EGR1 Antibody
Catalog Number: 31068
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O43638
Gene ID:2307
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to a region derived from 87-337 amino acids of human early growth response 1early growth response 1
- appl_detail:
- Predicted MW: 58kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
- other_names:
- early growth response 1, TIS8, AT225, G0S30, NGFI-A, ZNF225, KROX-24, ZIF-268
- Specificity:
- The antibody detects endogenous level of total EGR1 protein.
- Background:
- EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).
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