CNTFR Antibody

Catalog Number:

31061

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P24385
Gene ID:595

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 23-342 amino acids of human ciliary neurotrophic factor receptor

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CNTFR protein.

Applications:

ELISA WB

Background:

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

References:

appl_detail:

Predicted MW: 41kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF