Product Datasheet  
CNTFR Antibody  
Catalog Number: 31061  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P24385
    Gene ID:595
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a region derived from 23-342 amino acids of human ciliary neurotrophic factor receptor
  • reactivity：  
  • Hu Ms
  • appl_detail：  

  • Predicted MW: 41kd
    ELISA: 1:1000-1:5000
    Western blotting: 1:500-1:2000

  • other_names：  
  • ciliary neurotrophic factor receptor
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CNTFR protein.
  • Applications：  
  • ELISA WB
  • Background：  

  • This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.




 
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