CBX8 Antibody

Catalog Number:

31048

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99616
Gene ID:6357

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a C terminal 300 amino acids of human chromobox homolog 8

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CBX8 protein.

Applications:

ELISA WB IHC

Background:

Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

References:

appl_detail:

Predicted MW: 43kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50

Datasheet PDF