Product Datasheet  
CBX8 Antibody  
Catalog Number: 31048  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q99616
    Gene ID:6357
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to a C terminal 300 amino acids of human chromobox homolog 8
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 43kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:10-1:50
  • other_names：  
  • chromobox homolog 8, PC3, RC1
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CBX8 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.



 
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