CAPNS1 Antibody

Catalog Number:

31040

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P00915
Gene ID:759

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 91-268 amino acids of human calpain, small subunit 1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CAPNS1 protein.

Applications:

ELISA WB IHC

Background:

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

References:

appl_detail:

Predicted MW: 28kd
ELISA: 1:1000-1:2000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF