Product Datasheet
CAPNS1 Antibody
Catalog Number: 31040
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P00915
Gene ID:759
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to a region derived from 91-268 amino acids of human calpain, small subunit 1
- appl_detail:
- Predicted MW: 28kd
ELISA: 1:1000-1:2000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- calpain, small subunit 1, 30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4
- Specificity:
- The antibody detects endogenous level of total CAPNS1 protein.
- Applications:
- ELISA WB IHC
- Background:
- Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
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