VIM Antibody

Catalog Number:

31035

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P07384
Gene ID:823

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from 96-407 amino acids of Human Vimentin

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total VIM protein.

Applications:

ELISA WB

Background:

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

References:

appl_detail:

Predicted MW: 54kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000

Datasheet PDF