Product Datasheet
VIM Antibody
Catalog Number: 31035
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P07384
Gene ID:823
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Fusion protein corresponding to a region derived from 96-407 amino acids of Human Vimentin
- appl_detail:
- Predicted MW: 54kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
- Specificity:
- The antibody detects endogenous level of total VIM protein.
- Background:
- This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
© Signalway Biotechnology All Rights Reserved.