ALDOA Antibody

Catalog Number:

31028

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P08133
Gene ID:309

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to C terminal 200 amino acids of human aldolase A, fructose-bisphosphate

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total ALDOA protein.

Applications:

ELISA WB

Background:

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

References:

appl_detail:

Predicted MW: 39kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF