Product Datasheet  
ALDOA Antibody  
Catalog Number: 31028  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P08133
    Gene ID:309
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein corresponding to C terminal 200 amino acids of human aldolase A, fructose-bisphosphate
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 39kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
  • other_names：  
  • Aldolase A, fructose-bisphosphate, ALDA; GSD12
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total ALDOA protein.
  • Applications：  
  • ELISA WB
  • Background：  
  • The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.



 
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