CASP2 Antibody

Catalog Number:

31011

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P38936
Gene ID:1026

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to N terminal 201 amino acids of Human Caspase-2

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CASP2 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References:

appl_detail:

Predicted MW: 51kd
ELISA: 1:1000-1:10000
Western blotting: 1:1000-1:2000
Immunohistochemistry: 1:100-1:300

Datasheet PDF